I was visiting in Knoxville and stopped into a Tall Man Toys & Comics, a local shop near the Museum of Art. Putting the toys before comics in their name is accurate, as you can see from these photos, but they had a decent selection of new comics, with a buy 3, get 1 free discount, and the same graphic novel discount too, as well as good-sized back issue collection. The staff was quite nice, even when I left without buying anything, after I asked if they had anything produced locally (no). This is close to the University of Tennessee and the Worlds Fair Park, so I guess those two groups provide their customer base.
The Knoxville Museum of Art had an exhibit by woman artists with a superhero link as seen below. The museum is definitely a local one with no Western old masters, but there was a good glass exhibit, an excellent show by woman artist's and another good one of local artists and their history.